Professor Ruffleberg's Mansion is a location in Podunk, USA.
In 1965 it was home to Sidney Ruffleberg. Ruffleberg was conducting an experiment with a world of imagination, Evermore, and invited three of his closest friends to test it with him. However, the experiment went wrong and the three were trapped in Evermore. The mansion was abandoned for decades.
At the end of the game, the freed Ruffleberg and his friends have reappeared at the mansion.